SUBSTITUIERTE 1,3-DIAZOLYL-2-PROPANOLE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ANTIMYKOTISCHE MITTEL

1. Substituted 1,3-diazolyl-2-propanols of the general formula see diagramm : EP0118070,P10,F1 in which Alk**1 represents straight-chain or branched alkyl with 1 to 4 carbon atoms ; Alk**2 represents straight-chain or branched alkyl with 1 to 4 carbon atoms ; Alk**1 and Alk**2 together represents a...

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Hauptverfasser: REGEL,ERIK, SCHALLER,KLAUS,DR, PLEMPEL,MANFRED,DR, BUECHEL,KARL-HEINZ,DR, ELBE,HANS-LUDWIG,DR, HOLMWOOD,GRAHAM,DR
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creator REGEL,ERIK
SCHALLER,KLAUS,DR
PLEMPEL,MANFRED,DR
BUECHEL,KARL-HEINZ,DR
ELBE,HANS-LUDWIG,DR
HOLMWOOD,GRAHAM,DR
description 1. Substituted 1,3-diazolyl-2-propanols of the general formula see diagramm : EP0118070,P10,F1 in which Alk**1 represents straight-chain or branched alkyl with 1 to 4 carbon atoms ; Alk**2 represents straight-chain or branched alkyl with 1 to 4 carbon atoms ; Alk**1 and Alk**2 together represents a 3-to 7-membered cycloaliphatic ring ; X represents a nitrogen atom or the CH group ; Y represents a nitrogen atom or the CH group ; and R represents phenyl, phenylalkyl with 1 to 4 carbon atoms in the alkyl part, phenoxy, phenylthio, phenoxyalkyl with 1 to 4 carbon atoms in the alkyl part, phenylthioalkyl with 1 to 4 carbon atoms in the alkyl part, benzyloxy and benzylthio, each of which is optionally mono- to trisubstituted in the phenyl part by identical or different substituents, preferred substituents which may be mentioned being ; halogen, alkyl with 1 to 4 carbon atoms, alcoxy and alkylthio with in each case 1 to 4 carbon atoms, halogenoalkyl and halogenoalkoxy and halogenoalkylthio with in each case 1 to 2 carbon and 1 to 5 identical or different halogen atoms, such as preferably fluorine and chlorine atoms, nitro, cyano, hydroxyl, hydroxycarbonyl alkoxycarbonyl with 1 to 4 carbon atoms in the alkyl part, hydroxyiminoalkyl with 1 to 4 carbon atoms in the alkyl part, alkoxyiminoalkyl with 1 to 4 carbon atoms in each alkyl part, and phenyl, phenoxy, benzyl or benzyloxy, each of which is optionally substituted by halogen and/or alkyl with 1 to 2 carbon atoms, and physiologically tolerated acid addition salts thereof.
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Substituted 1,3-diazolyl-2-propanols of the general formula see diagramm : EP0118070,P10,F1 in which Alk**1 represents straight-chain or branched alkyl with 1 to 4 carbon atoms ; Alk**2 represents straight-chain or branched alkyl with 1 to 4 carbon atoms ; Alk**1 and Alk**2 together represents a 3-to 7-membered cycloaliphatic ring ; X represents a nitrogen atom or the CH group ; Y represents a nitrogen atom or the CH group ; and R represents phenyl, phenylalkyl with 1 to 4 carbon atoms in the alkyl part, phenoxy, phenylthio, phenoxyalkyl with 1 to 4 carbon atoms in the alkyl part, phenylthioalkyl with 1 to 4 carbon atoms in the alkyl part, benzyloxy and benzylthio, each of which is optionally mono- to trisubstituted in the phenyl part by identical or different substituents, preferred substituents which may be mentioned being ; halogen, alkyl with 1 to 4 carbon atoms, alcoxy and alkylthio with in each case 1 to 4 carbon atoms, halogenoalkyl and halogenoalkoxy and halogenoalkylthio with in each case 1 to 2 carbon and 1 to 5 identical or different halogen atoms, such as preferably fluorine and chlorine atoms, nitro, cyano, hydroxyl, hydroxycarbonyl alkoxycarbonyl with 1 to 4 carbon atoms in the alkyl part, hydroxyiminoalkyl with 1 to 4 carbon atoms in the alkyl part, alkoxyiminoalkyl with 1 to 4 carbon atoms in each alkyl part, and phenyl, phenoxy, benzyl or benzyloxy, each of which is optionally substituted by halogen and/or alkyl with 1 to 2 carbon atoms, and physiologically tolerated acid addition salts thereof.</abstract><oa>free_for_read</oa></addata></record>
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title SUBSTITUIERTE 1,3-DIAZOLYL-2-PROPANOLE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ANTIMYKOTISCHE MITTEL
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