SUBSTITUIERTE 1,3-DIAZOLYL-2-PROPANOLE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ANTIMYKOTISCHE MITTEL
1. Substituted 1,3-diazolyl-2-propanols of the general formula see diagramm : EP0118070,P10,F1 in which Alk**1 represents straight-chain or branched alkyl with 1 to 4 carbon atoms ; Alk**2 represents straight-chain or branched alkyl with 1 to 4 carbon atoms ; Alk**1 and Alk**2 together represents a...
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Zusammenfassung: | 1. Substituted 1,3-diazolyl-2-propanols of the general formula see diagramm : EP0118070,P10,F1 in which Alk**1 represents straight-chain or branched alkyl with 1 to 4 carbon atoms ; Alk**2 represents straight-chain or branched alkyl with 1 to 4 carbon atoms ; Alk**1 and Alk**2 together represents a 3-to 7-membered cycloaliphatic ring ; X represents a nitrogen atom or the CH group ; Y represents a nitrogen atom or the CH group ; and R represents phenyl, phenylalkyl with 1 to 4 carbon atoms in the alkyl part, phenoxy, phenylthio, phenoxyalkyl with 1 to 4 carbon atoms in the alkyl part, phenylthioalkyl with 1 to 4 carbon atoms in the alkyl part, benzyloxy and benzylthio, each of which is optionally mono- to trisubstituted in the phenyl part by identical or different substituents, preferred substituents which may be mentioned being ; halogen, alkyl with 1 to 4 carbon atoms, alcoxy and alkylthio with in each case 1 to 4 carbon atoms, halogenoalkyl and halogenoalkoxy and halogenoalkylthio with in each case 1 to 2 carbon and 1 to 5 identical or different halogen atoms, such as preferably fluorine and chlorine atoms, nitro, cyano, hydroxyl, hydroxycarbonyl alkoxycarbonyl with 1 to 4 carbon atoms in the alkyl part, hydroxyiminoalkyl with 1 to 4 carbon atoms in the alkyl part, alkoxyiminoalkyl with 1 to 4 carbon atoms in each alkyl part, and phenyl, phenoxy, benzyl or benzyloxy, each of which is optionally substituted by halogen and/or alkyl with 1 to 2 carbon atoms, and physiologically tolerated acid addition salts thereof. |
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