AMINOACRIDIN-(ALPHA)- UND/ODER (BETA)-(D)-N-GLYKOSID- UND/ODER AMINOACRIDIN-(ALPHA)- UND/ODER (BETA)-(L)-N-GLYKOSIDDERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL
The invention relates to novel aminoacridine- alpha , beta -(D)- and -(L)-N-glycoside derivatives, the salts thereof and to a novel process for the preparation of such compounds and salts. The novel compounds have the formula I I wherein R is hydrogen or a group of the formula II II wherein n=0 or 1...
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| creator | NANASI,PAL,DR JANOSSY,LORANT KOVACS,ANTAL,DR LIPTAK,ANDRAS,DR CSERNUS,ISTVAN KASZAB,ISTVAN,DR ERDEI,JANOS,DR NESZMELYI,ANDRAS,DR POLYA,KALMAN,DR |
| description | The invention relates to novel aminoacridine- alpha , beta -(D)- and -(L)-N-glycoside derivatives, the salts thereof and to a novel process for the preparation of such compounds and salts. The novel compounds have the formula I I wherein R is hydrogen or a group of the formula II II wherein n=0 or 1, p=1 or 2, A-p is an anion, preferably halogenide, R1 is hydrogen or a methyl group and R2 is hydrogen or a sugar residue, or R is dimethylamine, and the two substituents X and X1 are identical or different and stand for hydrogen, a group of the formula II, dimethylamine, halogen, a C1-4 alkyl group, a C1-4 alkoxy group, for a nitro-, cyano-, carbomethoxy-, carbamoyl-, phenyl- or a C1-4 alkylphenyl group, with the restriction that at least one of the substituents R, X and X1 represents a group of formula II with R2=sugar residue, and R3 is hydrogen or a C1-5 alkyl group. |
| format | Patent |
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The novel compounds have the formula I I wherein R is hydrogen or a group of the formula II II wherein n=0 or 1, p=1 or 2, A-p is an anion, preferably halogenide, R1 is hydrogen or a methyl group and R2 is hydrogen or a sugar residue, or R is dimethylamine, and the two substituents X and X1 are identical or different and stand for hydrogen, a group of the formula II, dimethylamine, halogen, a C1-4 alkyl group, a C1-4 alkoxy group, for a nitro-, cyano-, carbomethoxy-, carbamoyl-, phenyl- or a C1-4 alkylphenyl group, with the restriction that at least one of the substituents R, X and X1 represents a group of formula II with R2=sugar residue, and R3 is hydrogen or a C1-5 alkyl group.</description><language>ger</language><subject>CHEMISTRY ; DERIVATIVES THEREOF ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SUGARS</subject><creationdate>1982</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19820923&DB=EPODOC&CC=DE&NR=3207021A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19820923&DB=EPODOC&CC=DE&NR=3207021A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>NANASI,PAL,DR</creatorcontrib><creatorcontrib>JANOSSY,LORANT</creatorcontrib><creatorcontrib>KOVACS,ANTAL,DR</creatorcontrib><creatorcontrib>LIPTAK,ANDRAS,DR</creatorcontrib><creatorcontrib>CSERNUS,ISTVAN</creatorcontrib><creatorcontrib>KASZAB,ISTVAN,DR</creatorcontrib><creatorcontrib>ERDEI,JANOS,DR</creatorcontrib><creatorcontrib>NESZMELYI,ANDRAS,DR</creatorcontrib><creatorcontrib>POLYA,KALMAN,DR</creatorcontrib><title>AMINOACRIDIN-(ALPHA)- UND/ODER (BETA)-(D)-N-GLYKOSID- UND/ODER AMINOACRIDIN-(ALPHA)- UND/ODER (BETA)-(L)-N-GLYKOSIDDERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL</title><description>The invention relates to novel aminoacridine- alpha , beta -(D)- and -(L)-N-glycoside derivatives, the salts thereof and to a novel process for the preparation of such compounds and salts. The novel compounds have the formula I I wherein R is hydrogen or a group of the formula II II wherein n=0 or 1, p=1 or 2, A-p is an anion, preferably halogenide, R1 is hydrogen or a methyl group and R2 is hydrogen or a sugar residue, or R is dimethylamine, and the two substituents X and X1 are identical or different and stand for hydrogen, a group of the formula II, dimethylamine, halogen, a C1-4 alkyl group, a C1-4 alkoxy group, for a nitro-, cyano-, carbomethoxy-, carbamoyl-, phenyl- or a C1-4 alkylphenyl group, with the restriction that at least one of the substituents R, X and X1 represents a group of formula II with R2=sugar residue, and R3 is hydrogen or a C1-5 alkyl group.</description><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SUGARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1982</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjLsKAkEMRbexEPUfUq7g4GML66yJTnDMyuys4DYiMlaigv6lP-UIFpZWudx7TrrZCzeiFS68kKjJ0W0tDg00SuOK2ENeckhFTkOjZuX266oW-tn_1N2vngbZYeAR7Ngv0XpWaBuQFDxY9nVg5xpdfd4ACdf8AUtRSmViWYNFF1iJAX2rLBsJyelnnfPx8oiD7-1lsOSwsCbeb4f4uB9P8RqfB-JiNplPZlOcFn8gb9YETqA</recordid><startdate>19820923</startdate><enddate>19820923</enddate><creator>NANASI,PAL,DR</creator><creator>JANOSSY,LORANT</creator><creator>KOVACS,ANTAL,DR</creator><creator>LIPTAK,ANDRAS,DR</creator><creator>CSERNUS,ISTVAN</creator><creator>KASZAB,ISTVAN,DR</creator><creator>ERDEI,JANOS,DR</creator><creator>NESZMELYI,ANDRAS,DR</creator><creator>POLYA,KALMAN,DR</creator><scope>EVB</scope></search><sort><creationdate>19820923</creationdate><title>AMINOACRIDIN-(ALPHA)- UND/ODER (BETA)-(D)-N-GLYKOSID- UND/ODER AMINOACRIDIN-(ALPHA)- UND/ODER (BETA)-(L)-N-GLYKOSIDDERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL</title><author>NANASI,PAL,DR ; JANOSSY,LORANT ; KOVACS,ANTAL,DR ; LIPTAK,ANDRAS,DR ; CSERNUS,ISTVAN ; KASZAB,ISTVAN,DR ; ERDEI,JANOS,DR ; NESZMELYI,ANDRAS,DR ; POLYA,KALMAN,DR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_DE3207021A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>ger</language><creationdate>1982</creationdate><topic>CHEMISTRY</topic><topic>DERIVATIVES THEREOF</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SUGARS</topic><toplevel>online_resources</toplevel><creatorcontrib>NANASI,PAL,DR</creatorcontrib><creatorcontrib>JANOSSY,LORANT</creatorcontrib><creatorcontrib>KOVACS,ANTAL,DR</creatorcontrib><creatorcontrib>LIPTAK,ANDRAS,DR</creatorcontrib><creatorcontrib>CSERNUS,ISTVAN</creatorcontrib><creatorcontrib>KASZAB,ISTVAN,DR</creatorcontrib><creatorcontrib>ERDEI,JANOS,DR</creatorcontrib><creatorcontrib>NESZMELYI,ANDRAS,DR</creatorcontrib><creatorcontrib>POLYA,KALMAN,DR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>NANASI,PAL,DR</au><au>JANOSSY,LORANT</au><au>KOVACS,ANTAL,DR</au><au>LIPTAK,ANDRAS,DR</au><au>CSERNUS,ISTVAN</au><au>KASZAB,ISTVAN,DR</au><au>ERDEI,JANOS,DR</au><au>NESZMELYI,ANDRAS,DR</au><au>POLYA,KALMAN,DR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>AMINOACRIDIN-(ALPHA)- UND/ODER (BETA)-(D)-N-GLYKOSID- UND/ODER AMINOACRIDIN-(ALPHA)- UND/ODER (BETA)-(L)-N-GLYKOSIDDERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL</title><date>1982-09-23</date><risdate>1982</risdate><abstract>The invention relates to novel aminoacridine- alpha , beta -(D)- and -(L)-N-glycoside derivatives, the salts thereof and to a novel process for the preparation of such compounds and salts. The novel compounds have the formula I I wherein R is hydrogen or a group of the formula II II wherein n=0 or 1, p=1 or 2, A-p is an anion, preferably halogenide, R1 is hydrogen or a methyl group and R2 is hydrogen or a sugar residue, or R is dimethylamine, and the two substituents X and X1 are identical or different and stand for hydrogen, a group of the formula II, dimethylamine, halogen, a C1-4 alkyl group, a C1-4 alkoxy group, for a nitro-, cyano-, carbomethoxy-, carbamoyl-, phenyl- or a C1-4 alkylphenyl group, with the restriction that at least one of the substituents R, X and X1 represents a group of formula II with R2=sugar residue, and R3 is hydrogen or a C1-5 alkyl group.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS |
| title | AMINOACRIDIN-(ALPHA)- UND/ODER (BETA)-(D)-N-GLYKOSID- UND/ODER AMINOACRIDIN-(ALPHA)- UND/ODER (BETA)-(L)-N-GLYKOSIDDERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL |
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