AMINOACRIDIN-(ALPHA)- UND/ODER (BETA)-(D)-N-GLYKOSID- UND/ODER AMINOACRIDIN-(ALPHA)- UND/ODER (BETA)-(L)-N-GLYKOSIDDERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL

The invention relates to novel aminoacridine- alpha , beta -(D)- and -(L)-N-glycoside derivatives, the salts thereof and to a novel process for the preparation of such compounds and salts. The novel compounds have the formula I I wherein R is hydrogen or a group of the formula II II wherein n=0 or 1...

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Hauptverfasser: NANASI,PAL,DR, JANOSSY,LORANT, KOVACS,ANTAL,DR, LIPTAK,ANDRAS,DR, CSERNUS,ISTVAN, KASZAB,ISTVAN,DR, ERDEI,JANOS,DR, NESZMELYI,ANDRAS,DR, POLYA,KALMAN,DR
Format: Patent
Sprache:ger
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Zusammenfassung:The invention relates to novel aminoacridine- alpha , beta -(D)- and -(L)-N-glycoside derivatives, the salts thereof and to a novel process for the preparation of such compounds and salts. The novel compounds have the formula I I wherein R is hydrogen or a group of the formula II II wherein n=0 or 1, p=1 or 2, A-p is an anion, preferably halogenide, R1 is hydrogen or a methyl group and R2 is hydrogen or a sugar residue, or R is dimethylamine, and the two substituents X and X1 are identical or different and stand for hydrogen, a group of the formula II, dimethylamine, halogen, a C1-4 alkyl group, a C1-4 alkoxy group, for a nitro-, cyano-, carbomethoxy-, carbamoyl-, phenyl- or a C1-4 alkylphenyl group, with the restriction that at least one of the substituents R, X and X1 represents a group of formula II with R2=sugar residue, and R3 is hydrogen or a C1-5 alkyl group.