Verfahren zur Herstellung von Apovincaminsäureestern

Apovincaminic acid esters of the general formula (I> (wherein R and R independently represent alkyl groups having from 1 to 6 carbon atoms) may be prepared by reacting a hydroxyamino-E-homo- eburnane of the general formula (II> (wherein R and R are as defined above) or an acid addition salt th...

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Bibliographische Detailangaben
Hauptverfasser:	SZABO, LAJOS. DR., BUDAPEST, HU, VISKY, GYOERGY., BUDAPEST, HU, KREIDL, JANOS.., BUDAPEST, HU, SZANTAY, CSABA. DR., BUDAPEST, HU, FARKAS, GEB. KIRJAK, MARIA.., BUDAPEST, HU, CZIBULA, LASZLO.., BUDAPEST, HU, KALAUS, GYOERGY. DR., BUDAPEST, HU, NEMES, ANDRAS. DR., BUDAPEST, HU
Format:	Patent
Sprache:	ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Apovincaminic acid esters of the general formula (I> (wherein R and R independently represent alkyl groups having from 1 to 6 carbon atoms) may be prepared by reacting a hydroxyamino-E-homo- eburnane of the general formula (II> (wherein R and R are as defined above) or an acid addition salt thereof with an organic sulfonic acid, in an aprotic organic solvent. The compounds of the general formula (I) are useful pharmaceuticals.