DE3123295

Compounds of the formula wherein R1 is hydrogen or carboxy; Y is -CH2F, -CHF2, -CF3 or -C IDENTICAL CH; and Z is -(CH2)3-NH2, -CH(CH)3- (CH2)2-NH2 or -CH=CH-CH2- NH2; with the proviso that, when R1 is hydrogen, Z is -CH(CH3)-(CH2)2- NH2 and Y is not -CF3; or a lactam thereof when R1 is carboxy; and...

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Hauptverfasser: MCCANN, PETER P., CINCINNATI, OHIO, US, SJOERDSMA, ALBERT
Format: Patent
Sprache:eng
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Zusammenfassung:Compounds of the formula wherein R1 is hydrogen or carboxy; Y is -CH2F, -CHF2, -CF3 or -C IDENTICAL CH; and Z is -(CH2)3-NH2, -CH(CH)3- (CH2)2-NH2 or -CH=CH-CH2- NH2; with the proviso that, when R1 is hydrogen, Z is -CH(CH3)-(CH2)2- NH2 and Y is not -CF3; or a lactam thereof when R1 is carboxy; and their salts, are useful in inhibiting the growth of protozoa. They may be administered to animals, e.g. in their drinking water, and, if desired, together with an antiprotozoal agent.