PLASMINOGENPRAEPARAT UND VERFAHREN ZU SEINER HERSTELLUNG

A plasminogen preparation contains at least one of a physiologically acceptable inorganic salt, lysine, a salt thereof, phenylmethanesulfonyl fluoride, aprotinin, or soybean trypsin inhibitor in an amount effective for stabilizing plasminogen. The preparation may take the form of an aqueous solution...

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Bibliographische Detailangaben
Hauptverfasser:	FUNAKOSHI,SATOSHI, OHGAKI,MITSUOMI, URIYU,KATSUHIRO, WATANABE,RYOZO, UEMURA,YAHIRO
Format:	Patent
Sprache:	ger
Schlagworte:	BEER BIOCHEMISTRY CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ENZYMOLOGY HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	A plasminogen preparation contains at least one of a physiologically acceptable inorganic salt, lysine, a salt thereof, phenylmethanesulfonyl fluoride, aprotinin, or soybean trypsin inhibitor in an amount effective for stabilizing plasminogen. The preparation may take the form of an aqueous solution or a dry powder. The preparation can be prepared by adding the abovementioned stabilizer or stabilizers to an aqueous solution containing plasminogen, if necessary subjecting the resulting solution to digestion at 4 DEG to 37 DEG C at pH 2 to 4 for 20 to 60 minutes, and then to heat-treatment at 60 DEG C for 10 hours, and lyophilizing the resulting solution.