NEUE GLUCOPYRANOSE-NITROSOHARNSTOFFVERBINDUNGEN MIT ANTITUMORAKTIVITAET, VERFAHREN ZUR HERSTELLUNG DER VERBINDUNGEN UND DIESE ENTHALTENDES PHARMAZEUTISCHES MITTEL

New glucopyranose-nitrosourea compounds with antitumor activity are disclosed which have, as substituents, 2-chloroethyl- nitrosourea group as well as one member selected from branched-alkyl of 4-9 carbon atoms, cyclohexyl, methylcyclohexyl, benzyl methylphenyl, phenylethyl and normal-alkyl of 5-10...

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Hauptverfasser:	GORO,KIMURA, JUNZO,SEKINE
Format:	Patent
Sprache:	ger
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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creator	GORO,KIMURA JUNZO,SEKINE
description	New glucopyranose-nitrosourea compounds with antitumor activity are disclosed which have, as substituents, 2-chloroethyl- nitrosourea group as well as one member selected from branched-alkyl of 4-9 carbon atoms, cyclohexyl, methylcyclohexyl, benzyl methylphenyl, phenylethyl and normal-alkyl of 5-10 carbon atoms. These new compounds may be produced by reacting corresponding amino-glucopyranose compounds having amino or acid-added amino group with o-(or p-)nitro- or o-(or p-)cyano- phenyl N-(2-chlorethyl)- N-nitrosocarbamate compounds. Pharmaceutical compositions available for various tumor systems may be prepared by mixing physiologically acceptable carriers with the new compounds of the present invention.
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These new compounds may be produced by reacting corresponding amino-glucopyranose compounds having amino or acid-added amino group with o-(or p-)nitro- or o-(or p-)cyano- phenyl N-(2-chlorethyl)- N-nitrosocarbamate compounds. 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These new compounds may be produced by reacting corresponding amino-glucopyranose compounds having amino or acid-added amino group with o-(or p-)nitro- or o-(or p-)cyano- phenyl N-(2-chlorethyl)- N-nitrosocarbamate compounds. Pharmaceutical compositions available for various tumor systems may be prepared by mixing physiologically acceptable carriers with the new compounds of the present invention.</abstract><oa>free_for_read</oa></addata></record>
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subjects	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
title	NEUE GLUCOPYRANOSE-NITROSOHARNSTOFFVERBINDUNGEN MIT ANTITUMORAKTIVITAET, VERFAHREN ZUR HERSTELLUNG DER VERBINDUNGEN UND DIESE ENTHALTENDES PHARMAZEUTISCHES MITTEL
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