N ALPHA-ALKYLSULFONYLIERTE BZW. N ALPHA-ARYLSULFONYLIERTE OMEGA- AMIDINOPHENYL-ALPHA-AMINO-ALKYLCARBONSAEUREAMIDE, IHRE SAEUREADDITIONSSALZE UND VERFAHREN ZU IHRER HERSTELLUNG

N ALPHA-ALKYLSULFONYLIERTE BZW. N ALPHA-ARYLSULFONYLIERTE OMEGA- AMIDINOPHENYL-ALPHA-AMINO-ALKYLCARBONSAEUREAMIDE, IHRE SAEUREADDITIONSSALZE UND VERFAHREN ZU IHRER HERSTELLUNG

Compounds of the general formula:- wherein R is an alkylsulphonyl radical containing up to 6 carbon atoms or an arylsulphonyl radical containing 6 to 10 carbon atoms, R is a hydrogen atom, an alkyl radical containing up to 8 carbon atoms, an aryl radical containing 6 to 10 carbon atoms or an aralkyl...

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Hauptverfasser: HORN,HEIDEMARIE,ER.NAT, VOIGT,BERND,ER.NAT, MARKWARDT,FRITZ,DR.SC.MED.ER.NAT, WALSMANN,PETER,ER.NAT, WAGNER,GUENTHER,DR.SC.NAT, RICHTER,PETER,DR.SC.NAT
Format: Patent
Sprache:ger
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Compounds of the general formula:- wherein R is an alkylsulphonyl radical containing up to 6 carbon atoms or an arylsulphonyl radical containing 6 to 10 carbon atoms, R is a hydrogen atom, an alkyl radical containing up to 8 carbon atoms, an aryl radical containing 6 to 10 carbon atoms or an aralkyl radical containing up to 3 carbon atoms in the side chain, R is an alkyl radical containing up to 8 carbon atoms, an aryl radical containing 6 to 10 carbon atoms or an aralkyl radical containing up to 3 carbon atoms in the side chain, or R and R , together with the nitrogen atom to which they are attached, can also form a 5- to 7-membered heterocyclic ring-which can contain one or more further heteroatoms and/or can be substituted and n is 0, 1, 2 or 3; as well as the acid-addition salts thereof with physiologically acceptable inorganic and organic acids have anticoagulant activity.