PHOSPHONYLUREIDOBENZOL-DERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL

PHOSPHONYLUREIDOBENZOL-DERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL

The invention includes phosphonylureidobenzene compounds of the general formula (I) or pharmaceutically acceptable salts in which R1 and R2 are identical or different and represent an alkyl group, or R1 and R2 together represent a dimethylene group, a trimethylene group or a tetramethylene group, X...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WOLLWEBER,HARTMUND,.DR, THOMAS,HERBERT,DR, ANDREWS,PETER,DR
Format: Patent
Sprache:ger
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention includes phosphonylureidobenzene compounds of the general formula (I) or pharmaceutically acceptable salts in which R1 and R2 are identical or different and represent an alkyl group, or R1 and R2 together represent a dimethylene group, a trimethylene group or a tetramethylene group, X and Y are identical or different and represent an oxygen atom or a sulphur atom and R3 and R4 are identical or different and represent an alkyl group, or R3 and R4 together represent a trimethylene group or a tetramethylene group, or R3 and R4, together with the carbon atom and nitrogen atom between them, form a thiazolidine ring system, which are used medicinally as parasiticides. The compounds are particularly effective in combatting helminths in carnivores. Also included in the invention are pharmaceutical compositions containing said phosphonylureidobenzene compounds and methods for the treatment of warm-blooded animals by administering said compounds or compositions.