DE2717811

The amino group-containing polyene macrolide is reacted with a mono- or oligosaccharide of the aldose or ketose series in an organic solvent or an organic solvent mixture. In order to be able to use an inexpensive, non-flammable solvent, the N-glycosyl derivative produced is precipitated from the re...

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Hauptverfasser: PLOCIENNIK, GEB. MAKAROWSKA, ZOFIA-PHARMAZEUT, WARSZAWA, PL, GOLIK, JERZY, BOROWSKI, JAN, DR..., GDANSK, PL, BYLEC, ELZBIETA., GDANSK, PL, ZIELINSKI, JAN..., GDANSK, PL, DAHLIG, GEB. BOJARSKA, HALINA, DR..., WARSZAWA, PL, PAWLAK, JAN.., SOPOT, PL, FALKOWSKI, LEONARD..., GDANSK, PL, JAKOBS, GEB. ZABLOCKA, EWA.BIOL., SOPOT, PL, WAGNER, GEB. TOMASZEWSKA, WLADYSLAWA, WARSZAWA, PL, KOWSZYK-GINDIFER, ZUZANNA, KOLODZIEJCZYK, PAWEL, ROSLIK-KAMINSKA, GEB. SIKORSKA, DANUTA.BIOL
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Sprache:eng
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Zusammenfassung:The amino group-containing polyene macrolide is reacted with a mono- or oligosaccharide of the aldose or ketose series in an organic solvent or an organic solvent mixture. In order to be able to use an inexpensive, non-flammable solvent, the N-glycosyl derivative produced is precipitated from the reaction medium by means of water or an aqueous solution of an inorganic salt, purified by crystallisation from a higher alcohol, and optionally converted into a salt.