6,7-BENZOMORPHANE, VERFAHREN ZU DEREN HERSTELLUNG UND DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL

The invention is concerned with certain novel 6,7-benzomorphan derivatives having analgesic and/or morphine-antagonistic properties of the formula wherein each R is a lower alkyl group; R1 is a hydrogen atom, or an alkyl, haloalkyl, alkenyl, haloalkenyl, alkinyl, cycloalkyl, cycloalkenyl, cycloalkyl...

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Bibliographische Detailangaben
Hauptverfasser:	VAN LEEUWEN,GEERTRUIDA C, M. AKKERMAN,ANTONY
Format:	Patent
Sprache:	ger
Schlagworte:	BLASTING BRAKES CHEMISTRY CLUTCHES COUPLINGS FOR TRANSMITTING ROTATION ENGINEERING ELEMENTS AND UNITS GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVEFUNCTIONING OF MACHINES OR INSTALLATIONS HEATING HETEROCYCLIC COMPOUNDS LIGHTING MECHANICAL ENGINEERING METALLURGY ORGANIC CHEMISTRY THERMAL INSULATION IN GENERAL WEAPONS
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Beschreibung
Zusammenfassung:	The invention is concerned with certain novel 6,7-benzomorphan derivatives having analgesic and/or morphine-antagonistic properties of the formula wherein each R is a lower alkyl group; R1 is a hydrogen atom, or an alkyl, haloalkyl, alkenyl, haloalkenyl, alkinyl, cycloalkyl, cycloalkenyl, cycloalkylalkyl, cycloalkenylalkyl, cycloalkylidenealkyl, aralkyl, heteroarylalkyl or heterocycloalkylalkyl group; R2 is a hydrogen atom or a hydroxy, alkoxy, alkoxyalkoxy or acyloxy group. Such 6,7-benzomorphans may be in the form of their optically active enantiomers and/or their therapeutically acceptable salts. Methods for producing such 6,7-benzomorphan derivatives, and novel intermediates useful for such production are also disclosed and form part of the invention.