SUBSTITUIERTE 2,6-DIAMINO-ANTHRACHINONE UND VERFAHREN ZU IHRER HERSTELLUNG

SUBSTITUIERTE 2,6-DIAMINO-ANTHRACHINONE UND VERFAHREN ZU IHRER HERSTELLUNG

New derivs. are of formula (I): (where R1 is H or Me; R2 and R3 are both H or both Me, or R2 is H and R3 is 1-4C alkyl). (I) and their acid addn. salts have antiprotozoal activity and can be used to treat amoebic infestations (e.g. due to Entamoeba histolytica) in humans and animals. They also have...

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Bibliographische Detailangaben
Hauptverfasser: RAETHER,WOLFGANG,DR, WINKELMANN,ERHARDT,DR, ROLLY,HEINRICH,DR
Format: Patent
Sprache:ger
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:New derivs. are of formula (I): (where R1 is H or Me; R2 and R3 are both H or both Me, or R2 is H and R3 is 1-4C alkyl). (I) and their acid addn. salts have antiprotozoal activity and can be used to treat amoebic infestations (e.g. due to Entamoeba histolytica) in humans and animals. They also have interferon-inducing activity and are thus active against viruses, esp. influenza and encephalomyocarditis viruses. A typical cpd. is 2,6-bis(dimethylaminoacetylamino)-anthraquinone, prepd. e.g. by reacting 2,6-bis (chloroacetylamino)-anthraquinone with MeNH.