DE2527937

2-Oxyindole derivatives represented by the following general formula: where R1 is selected from the group consisting of hydrogen, C1-4 alkyl, C2-4 alkenyl, benzyl and phenethyl; A is -CH=CH- or wherein R2 or R3 may be the same or different and are selected from the group consisting of hydrogen and C...

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Hauptverfasser: OKA, KIMIAKI, TOKUSHIMA, JP, NAKAGAWA, KAZUYUKI, TOKUSHIMA, JP, UCHIMA, MINORU, KOMATSUSHIMA, JP
Format: Patent
Sprache:eng
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Zusammenfassung:2-Oxyindole derivatives represented by the following general formula: where R1 is selected from the group consisting of hydrogen, C1-4 alkyl, C2-4 alkenyl, benzyl and phenethyl; A is -CH=CH- or wherein R2 or R3 may be the same or different and are selected from the group consisting of hydrogen and C1-4 alkyl; R4 is -OR5, wherein R5 is selected from the group consisting of hydrogen, C1-8 alkyl, cyclohexyl, benzyl and phenethyl, or wherein R6 and R7 may be the same or different and are selected from the group consisting of hydrogen, C1-4 alkyl, benzyl, phenethyl and together with the nitrogen atom, a heterocyclic group selected from the group consisting of a piperidino, morpholino, piperazino or thiazolino group; and m and n each are zero or a positive integer with m+n being no more than 11. The 2-oxyindole derivatives have excellent effects on the inhibition of platelet aggregation.