D-GLYKOSAMINSALZE MIT THERAPEUTISCHER WIRKUNG

D-GLYKOSAMINSALZE MIT THERAPEUTISCHER WIRKUNG

For the treatment of cardiac hypertrophy, d-glucosamine salts of the 3',5'-adenosine monophosphoric cyclic acid (AMP-c) and of the dibutyl ester thereof are disclosed, these salts having a reduced acute toxicity and an improved activity on the mitochondria of hypertrophic heart with respec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ROSSI,GIACINTO, REINER,ALBERTO
Format: Patent
Sprache:ger
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Beschreibung
Zusammenfassung:For the treatment of cardiac hypertrophy, d-glucosamine salts of the 3',5'-adenosine monophosphoric cyclic acid (AMP-c) and of the dibutyl ester thereof are disclosed, these salts having a reduced acute toxicity and an improved activity on the mitochondria of hypertrophic heart with respect to the cyclic AMP acid alone or its dibutyl ester. The compounds in question are useful for the treatment of cardiac hypertrophy and alteration of the energetic muscular metabolism.