Enzyme-regulating and cardiovascular compsns - contg. acylated anilinobutyric acids eg to increase prodn. of pancreatic and gastric enzymes

Compsn. for regulating gastrointestinal enzymes and having cardiovascular analeptic activity contains an acylated anilinobutyric acid of formula (I) (R1-R5=H, 1-4C alkyl, alkoxy or alkylthio, halo or CF3; R3 can alos be OH or PhCH20; Y= is not >6C alkyl or cycloalky or opt. substd. is not >16C...

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Hauptverfasser: SCHOETENSACK,WOLFGANG,DR, RIEDEL,RICHARD,DR
Format: Patent
Sprache:eng ; ger
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Zusammenfassung:Compsn. for regulating gastrointestinal enzymes and having cardiovascular analeptic activity contains an acylated anilinobutyric acid of formula (I) (R1-R5=H, 1-4C alkyl, alkoxy or alkylthio, halo or CF3; R3 can alos be OH or PhCH20; Y= is not >6C alkyl or cycloalky or opt. substd. is not >16C aryl; Z=H or an equiv. of a salt-forming cation). Pref. cpds. have R1-R5=1-2C alkyl or alkoxy, Cl or CF3;R3 may also be OH or PhCH2O; Y=1-2c alkyl or phenyl opt. substd. by Cl; Z=H or an equiv. of Na, K, Ca, Mg, Al, glucosamine, N-methylglucosamine, mono-di-or-tri-ethanolamine or ethylenediamine.