VERFAHREN ZUR HERSTELLUNG VON L-ASPARAGINSAEURESALZ DES ZYKLISCHEN KARBONATS VON ERYTHROMYCIN A UND EIN PHARMAZEUTISCHES NACH DIESEM VERFAHREN HERGESTELLTES MITTEL

1443097 L-Aspartate of cyclic erythromycin A 6,9-hemiacetal carbonate INSTYTUT PRZEMYSLU FARMACEUTYCZNEGO 22 July 1974 [28 July 1973] 32396/74 Heading C2C The novel antibiotic, the L-aspartate of cyclic erythromycin A 6,9-hemiacetal carbonate is obtained, optionally as the monohydrate, by reacting s...

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Hauptverfasser:	DAHLIG GEB. BOJARSKA, HALINA, DR, SZYPKA, ZDZISLAW
Format:	Patent
Sprache:	ger
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Zusammenfassung:	1443097 L-Aspartate of cyclic erythromycin A 6,9-hemiacetal carbonate INSTYTUT PRZEMYSLU FARMACEUTYCZNEGO 22 July 1974 [28 July 1973] 32396/74 Heading C2C The novel antibiotic, the L-aspartate of cyclic erythromycin A 6,9-hemiacetal carbonate is obtained, optionally as the monohydrate, by reacting substantially stoichiometric proportions of the cyclic carbonate of erythromycin A 6,9-hemiacetal and L-aspartic acid in an aqueous medium (e.g. H 2 O, H 2 O/acetone, H 2 O/ethanol). To isolate the product, the resulting solution may be lyophilized or evaporated with, if necessary, addition of a liquid which forms a binary or ternary azeotropic mixture therewith.