DE2434017
1473090 Cephalosporins LILLY INDUSTRIES Ltd 18 July 1974 [19 July 1973] 34337/73 Heading C2C A 7 - α - aminoacetamido - cephalosporin - 4- carboxylic acid is made by reacting a 7-aminocephalosporin-4-carboxylic acid ester with a reactive derivative of an α-aminoacetic acid, in which the amino group...
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| creator | SPENCE, THOMAS WILLIAM MATCHES, GREAT SANKEY, WARRINGTON, CHESHIRE DAVISON, MICHAEL, RAINFORD, ST. HELENS, LANCASHIRE FRANKHAM, DAVID BINFIELD, HELSBY, WARRINGTON |
| description | 1473090 Cephalosporins LILLY INDUSTRIES Ltd 18 July 1974 [19 July 1973] 34337/73 Heading C2C A 7 - α - aminoacetamido - cephalosporin - 4- carboxylic acid is made by reacting a 7-aminocephalosporin-4-carboxylic acid ester with a reactive derivative of an α-aminoacetic acid, in which the amino group is protected by forming an enamine with a #-dicarbonyl compound; removing the amino protecting group from the product; adding sufficient hydrazine or its derivative (e.g. semicarbazide) to prevent reaction of the liberated dicarbonyl compound; and, if desired de-esterifying the resulting 7-α- aminoacetamido compound. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | DE2434017 |
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