VERFAHREN ZUR HERSTELLUNG NEUER BISPIPERAZINO-ANDROSTAN-DERIVATE

Title cpds. (I) their salts and quaternary ammonium salts. (where R is H, or 1-6C acyl, R1 is 1-6C alkyl, vinyl, allyl, or hydroxyethyl, R2 is H, 1-6C-alkyl, allyl or benzyl, X is H Y is OH or 1-6C acyloxy or X + Y is O and salt forming anions are Cl, Br, I, OH, mesyloxy or tosyloxy) are prepd. by r...

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Hauptverfasser: KARPATI,EGON,DR, SZEBERENYI,SZABOLCS,DR, SZPORNY,LASZLO,DR, TUBA,ZOLTAN,DR, SZEPESI,GABOR,.DR, SZABO,MARIA,. BOR GEB
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Sprache:ger
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Zusammenfassung:Title cpds. (I) their salts and quaternary ammonium salts. (where R is H, or 1-6C acyl, R1 is 1-6C alkyl, vinyl, allyl, or hydroxyethyl, R2 is H, 1-6C-alkyl, allyl or benzyl, X is H Y is OH or 1-6C acyloxy or X + Y is O and salt forming anions are Cl, Br, I, OH, mesyloxy or tosyloxy) are prepd. by reacting a 2 alpha, 3 alpha, 16 alpha, 17 alpha diepoxy-5 alpha-androstane with and then opt. reducing and/or a acylating the product.