Aldonic acid amides and medicaments contg. them - as analgesic antiinflammatory and vaso dilating agents galvano plastic and polymer auxiliaries

Aldonic acid amides and medicaments contg. them - as analgesic antiinflammatory and vaso dilating agents galvano plastic and polymer auxiliaries

The title amides are of formula (I): (where R1 is a (4-10)C aliphatic residue opt. interrupted by O or S and/or carrying an OH gp, any gp or heteroatom being sepd. from CONH by >=2C: R2 is H or 1-3C aliphatic residue opt. substd. by phosphinyl opt. carrying alkyl, hydroxylakyl and/or alkoxy-alkyl...

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Bibliographische Detailangaben
Hauptverfasser: SCHULTES, ERNST, HEMPEL, WOLFGANG, SOEDER, ALFONS. DR, REISER, MARIO
Format: Patent
Sprache:eng ; ger
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:The title amides are of formula (I): (where R1 is a (4-10)C aliphatic residue opt. interrupted by O or S and/or carrying an OH gp, any gp or heteroatom being sepd. from CONH by >=2C: R2 is H or 1-3C aliphatic residue opt. substd. by phosphinyl opt. carrying alkyl, hydroxylakyl and/or alkoxy-alkyl (each alkyl or alkoxy contg. 1-3C); n is 3-5 and X is OH or H) are prepd. by reacting an alclonic acid lactone or ester with R1R2NH. The d (+)-gluconic acid 2-(+)-heptylamide is prepd. from (+)-2-amino heptane and d (+)-gluconic acid.