4'-oxo-rhamnosyl-glycosides - cardiotonics with improved resorption
Title cpds. of formula (I): (where R1 and R2 are H or R1 and R2 is in which A is H or lower alkyl and B is lower alkyl or phenyl, or CAB is a 6- or 7-membered cycloaliphatic ring; R3 and R4 are H or R3 + R4 is oxo; R5 is the cardenolide ring or the bufadienolide ring; and R6 is H and R7 is OH or H,...
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| creator | KOBINGER,WALTER,DR HEIDER,JOACHIM,.DR EBERLEIN,WOLFGANG,.DR |
| description | Title cpds. of formula (I): (where R1 and R2 are H or R1 and R2 is in which A is H or lower alkyl and B is lower alkyl or phenyl, or CAB is a 6- or 7-membered cycloaliphatic ring; R3 and R4 are H or R3 + R4 is oxo; R5 is the cardenolide ring or the bufadienolide ring; and R6 is H and R7 is OH or H, when R5 is the cardenolide ring, or together with R6 signifies a double bond), which have good cardiotonic activity with better resorption than corresp. non-oxidised rhamnosyl-glycosides, and which are also as intermediates for a variety of other cardioglycoside derivs. |
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R3 and R4 are H or R3 + R4 is oxo; R5 is the cardenolide ring or the bufadienolide ring; and R6 is H and R7 is OH or H, when R5 is the cardenolide ring, or together with R6 signifies a double bond), which have good cardiotonic activity with better resorption than corresp. non-oxidised rhamnosyl-glycosides, and which are also as intermediates for a variety of other cardioglycoside derivs.</description><language>eng ; ger</language><subject>CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY ; STEROIDS</subject><creationdate>1972</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19720302&DB=EPODOC&CC=DE&NR=2042075A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19720302&DB=EPODOC&CC=DE&NR=2042075A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KOBINGER,WALTER,DR</creatorcontrib><creatorcontrib>HEIDER,JOACHIM,.DR</creatorcontrib><creatorcontrib>EBERLEIN,WOLFGANG,.DR</creatorcontrib><title>4'-oxo-rhamnosyl-glycosides - cardiotonics with improved resorption</title><description>Title cpds. of formula (I): (where R1 and R2 are H or R1 and R2 is in which A is H or lower alkyl and B is lower alkyl or phenyl, or CAB is a 6- or 7-membered cycloaliphatic ring; R3 and R4 are H or R3 + R4 is oxo; R5 is the cardenolide ring or the bufadienolide ring; and R6 is H and R7 is OH or H, when R5 is the cardenolide ring, or together with R6 signifies a double bond), which have good cardiotonic activity with better resorption than corresp. non-oxidised rhamnosyl-glycosides, and which are also as intermediates for a variety of other cardioglycoside derivs.</description><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>STEROIDS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1972</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyjEOwjAMAMAsDKjwB29MkUop6ozaIh7AXkWJoZbSOLIjoL9n4QFMt9zW9O3B8oetzG5JrGu0z7h6VgqoYME7CcSFE3mFN5UZaMnCLwwgqCy5EKed2TxcVNz_rAxcx3t_s5h5Qs3OY8IyDWNTt03dnS_H0x_lCyJ2MjM</recordid><startdate>19720302</startdate><enddate>19720302</enddate><creator>KOBINGER,WALTER,DR</creator><creator>HEIDER,JOACHIM,.DR</creator><creator>EBERLEIN,WOLFGANG,.DR</creator><scope>EVB</scope></search><sort><creationdate>19720302</creationdate><title>4'-oxo-rhamnosyl-glycosides - cardiotonics with improved resorption</title><author>KOBINGER,WALTER,DR ; HEIDER,JOACHIM,.DR ; EBERLEIN,WOLFGANG,.DR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_DE2042075A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; ger</language><creationdate>1972</creationdate><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>STEROIDS</topic><toplevel>online_resources</toplevel><creatorcontrib>KOBINGER,WALTER,DR</creatorcontrib><creatorcontrib>HEIDER,JOACHIM,.DR</creatorcontrib><creatorcontrib>EBERLEIN,WOLFGANG,.DR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KOBINGER,WALTER,DR</au><au>HEIDER,JOACHIM,.DR</au><au>EBERLEIN,WOLFGANG,.DR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>4'-oxo-rhamnosyl-glycosides - cardiotonics with improved resorption</title><date>1972-03-02</date><risdate>1972</risdate><abstract>Title cpds. of formula (I): (where R1 and R2 are H or R1 and R2 is in which A is H or lower alkyl and B is lower alkyl or phenyl, or CAB is a 6- or 7-membered cycloaliphatic ring; 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| subjects | CHEMISTRY METALLURGY ORGANIC CHEMISTRY STEROIDS |
| title | 4'-oxo-rhamnosyl-glycosides - cardiotonics with improved resorption |
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