3D-Matrix zur Herstellung von Zelltransplantaten

The invention relates to a method for producing a biologically compatible matrix, to a matrix that can be obtained using the method, and to the use thereof. The invention also relates to an implant. The inventive matrix can be produced by dissolving, in water, chitosan in acid, by freezing the solut...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HAHNEMANN, BIRGER, PAHMEIER, ANDREA, LOETZBEYER, THOMAS
Format: Patent
Sprache:ger
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Beschreibung
Zusammenfassung:The invention relates to a method for producing a biologically compatible matrix, to a matrix that can be obtained using the method, and to the use thereof. The invention also relates to an implant. The inventive matrix can be produced by dissolving, in water, chitosan in acid, by freezing the solution and by subsequently lyophilizing the same. Excess acid can be removed by neutralizing with a base before or after the lyophilization. The inventive matrix is dimensionally stable and elastic. When implanted, it induces only a minor immunoreaction.