Polyurethane articles containing antibiotic

Moulded articles comprising an antibiotic homogeneously dispersed in a thermoplastic polyurethane are claimed, where the articles (a) have a surface roughness (peak-to-valley height) of less than 5 mu m or (b) have a greater tensile strength that articles made from the corresponding antibiotic-free...

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Hauptverfasser: PUDLEINER, HEINZ. DR., 47800 KREFELD, DE, ALBERS, REINHARD. DR., 51375 LEVERKUSEN, DE, KREIS, WOLFGANG. DR., 51467 BERGISCH GLADBACH, DE, EBERZ, GUENTHER-BIOL. DR., 51375 LEVERKUSEN, DE, SIMON, JOACHIM. DR., 40589 DUESSELDORF, DE, KRASEMANN, CHRISTINA, DR., 40724 HILDEN, DE, DUJARDIN, RALF. DR., NOVI, MICH., US
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creator PUDLEINER, HEINZ. DR., 47800 KREFELD, DE
ALBERS, REINHARD. DR., 51375 LEVERKUSEN, DE
KREIS, WOLFGANG. DR., 51467 BERGISCH GLADBACH, DE
EBERZ, GUENTHER-BIOL. DR., 51375 LEVERKUSEN, DE
SIMON, JOACHIM. DR., 40589 DUESSELDORF, DE
KRASEMANN, CHRISTINA, DR., 40724 HILDEN, DE
DUJARDIN, RALF. DR., NOVI, MICH., US
description Moulded articles comprising an antibiotic homogeneously dispersed in a thermoplastic polyurethane are claimed, where the articles (a) have a surface roughness (peak-to-valley height) of less than 5 mu m or (b) have a greater tensile strength that articles made from the corresponding antibiotic-free polyurethane. Also claimed are processes for producing articles as above, comprising (1) extruding or injection-moulding a homogeneous dispersion of the antibiotic in the polyurethane or (2) coextruding the antibiotic and polyurethane. Also claimed is a process for producing a thermoplastic polyurethane containing a homogeneously dispersed antibiotic, comprising mixing the antibiotic with the polyurethane. Also claimed is a thermoplastic polyurethane that is obtainable by reaction of polytetrahydrofuran, isophorone diisocyanate, isophorone diamine and 1,6-hexanediol and contains homogeneously dispersed ciprofloxacin.
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Also claimed is a process for producing a thermoplastic polyurethane containing a homogeneously dispersed antibiotic, comprising mixing the antibiotic with the polyurethane. Also claimed is a thermoplastic polyurethane that is obtainable by reaction of polytetrahydrofuran, isophorone diisocyanate, isophorone diamine and 1,6-hexanediol and contains homogeneously dispersed ciprofloxacin.</description><edition>6</edition><language>eng ; ger</language><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES ; CHEMISTRY ; COMPOSITIONS BASED THEREON ; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ; HUMAN NECESSITIES ; HYGIENE ; MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS ; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ; ORGANIC MACROMOLECULAR COMPOUNDS ; THEIR PREPARATION OR CHEMICAL WORKING-UP ; USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS</subject><creationdate>1999</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19990708&amp;DB=EPODOC&amp;CC=DE&amp;NR=19812160C1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19990708&amp;DB=EPODOC&amp;CC=DE&amp;NR=19812160C1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PUDLEINER, HEINZ. 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Also claimed are processes for producing articles as above, comprising (1) extruding or injection-moulding a homogeneous dispersion of the antibiotic in the polyurethane or (2) coextruding the antibiotic and polyurethane. Also claimed is a process for producing a thermoplastic polyurethane containing a homogeneously dispersed antibiotic, comprising mixing the antibiotic with the polyurethane. 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DR., 47800 KREFELD, DE</creatorcontrib><creatorcontrib>ALBERS, REINHARD. DR., 51375 LEVERKUSEN, DE</creatorcontrib><creatorcontrib>KREIS, WOLFGANG. DR., 51467 BERGISCH GLADBACH, DE</creatorcontrib><creatorcontrib>EBERZ, GUENTHER-BIOL. DR., 51375 LEVERKUSEN, DE</creatorcontrib><creatorcontrib>SIMON, JOACHIM. DR., 40589 DUESSELDORF, DE</creatorcontrib><creatorcontrib>KRASEMANN, CHRISTINA, DR., 40724 HILDEN, DE</creatorcontrib><creatorcontrib>DUJARDIN, RALF. DR., NOVI, MICH., US</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PUDLEINER, HEINZ. DR., 47800 KREFELD, DE</au><au>ALBERS, REINHARD. DR., 51375 LEVERKUSEN, DE</au><au>KREIS, WOLFGANG. DR., 51467 BERGISCH GLADBACH, DE</au><au>EBERZ, GUENTHER-BIOL. DR., 51375 LEVERKUSEN, DE</au><au>SIMON, JOACHIM. DR., 40589 DUESSELDORF, DE</au><au>KRASEMANN, CHRISTINA, DR., 40724 HILDEN, DE</au><au>DUJARDIN, RALF. DR., NOVI, MICH., US</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Polyurethane articles containing antibiotic</title><date>1999-07-08</date><risdate>1999</risdate><abstract>Moulded articles comprising an antibiotic homogeneously dispersed in a thermoplastic polyurethane are claimed, where the articles (a) have a surface roughness (peak-to-valley height) of less than 5 mu m or (b) have a greater tensile strength that articles made from the corresponding antibiotic-free polyurethane. Also claimed are processes for producing articles as above, comprising (1) extruding or injection-moulding a homogeneous dispersion of the antibiotic in the polyurethane or (2) coextruding the antibiotic and polyurethane. Also claimed is a process for producing a thermoplastic polyurethane containing a homogeneously dispersed antibiotic, comprising mixing the antibiotic with the polyurethane. Also claimed is a thermoplastic polyurethane that is obtainable by reaction of polytetrahydrofuran, isophorone diisocyanate, isophorone diamine and 1,6-hexanediol and contains homogeneously dispersed ciprofloxacin.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record>
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subjects CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
CHEMISTRY
COMPOSITIONS BASED THEREON
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
HUMAN NECESSITIES
HYGIENE
MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METALLURGY
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
ORGANIC MACROMOLECULAR COMPOUNDS
THEIR PREPARATION OR CHEMICAL WORKING-UP
USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS
title Polyurethane articles containing antibiotic
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