Onkogen- oder virusgesteuerte Expressionssysteme

Nucleic acid construct (A) comprises a promoter for expressing an effector gene (I), and a promoter for regulating expression of transcription factor gene (II), where protein (II) binds the promoter of (I) to control expression. The activity of the protein (II) depends on cellular regulatory protein...

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Bibliographische Detailangaben
Hauptverfasser: SEDLACEK, HANS-HARALD, DR., 35041 MARBURG, DE, MUELLER, ROLF, DR., 35037 MARBURG, DE
Format: Patent
Sprache:ger
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Zusammenfassung:Nucleic acid construct (A) comprises a promoter for expressing an effector gene (I), and a promoter for regulating expression of transcription factor gene (II), where protein (II) binds the promoter of (I) to control expression. The activity of the protein (II) depends on cellular regulatory protein(s) which specifically bind to and modify its activity. Independent claims are also included for the following: (1) vector containing (A); and (2) isolated cells containing (A) or the vector.