New bipyridinium compounds useful as vascular endothelial cell growth factor blockers

New bipyridinium compounds useful as vascular endothelial cell growth factor blockers

Bipyridinium compounds (I) are new. Bipyridinium compounds of formula (I) are new. R1, R3, R6, R8 = H, 1-6C alkyl, COCH3 or CO2CH3; R2, R4, R5, R7, R9, R10 = H, OH or CO2CH3; alkylene1, alkylene2 = 2-5C alkylene; X = F, Cl, Br or I; Provided that when X = Br and the alkylene groups are ethylene, the...

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Hauptverfasser: KRUEGER, MARTIN., 13465 BERLIN, DE, THIERAUCH, KARL-HEINZ., 14169 BERLIN, DE, PRIBILLA, IRIS., 14055 BERLIN, DE, SCHIRNER, MICHAEL., 13156 BERLIN, DE, MARTINY-BARON, GEORG., 79336 HERBOLZHEIM, DE, SEIDELMANN, DIETER., 12159 BERLIN, DE, MENRAD, ANDREAS., 16515 ORANIENBURG, DE
Format: Patent
Sprache:eng ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Bipyridinium compounds (I) are new. Bipyridinium compounds of formula (I) are new. R1, R3, R6, R8 = H, 1-6C alkyl, COCH3 or CO2CH3; R2, R4, R5, R7, R9, R10 = H, OH or CO2CH3; alkylene1, alkylene2 = 2-5C alkylene; X = F, Cl, Br or I; Provided that when X = Br and the alkylene groups are ethylene, then R1-R10 are not H.