New nucleic acid encoding nCL-3 calpain

The murine cDNA (I) for nCL-3 calpain of 2459 bp, its allelic variants encoding a protein having 60-100% homology at the amino acid (aa) level, analogues and derivatives are new. Also new are: (1) the corresponding human cDNA (Ia) of 1975 bp; (2) gene constructs containing (I) and (Ia) plus regulato...

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Hauptverfasser: BOEHM, THOMAS, DR., 79279 VOERSTETTEN, DE, NEIL, T. DEAR., 69123 HEIDELBERG, DE
Format: Patent
Sprache:eng ; ger
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Zusammenfassung:The murine cDNA (I) for nCL-3 calpain of 2459 bp, its allelic variants encoding a protein having 60-100% homology at the amino acid (aa) level, analogues and derivatives are new. Also new are: (1) the corresponding human cDNA (Ia) of 1975 bp; (2) gene constructs containing (I) and (Ia) plus regulatory sequences; and (3) proteins (II) encoded by (I).