1-(3-hydroxymethyl-phenoxy)-2-hydroxy-3 sec - -butylaminopropane - prepd from substd epoxypropane and butylamine sh

Title cpd. (I) and its acid-addn. salts, are pref. pred. by reacting a cpd. (II): with sec. butylamine in ethanol (whwere Z is or -CH(OH)-CH2-hal). Cpd. (I) may be used in treatment and prophylaxis of coronary diseases and in the treatment of heart arrythmias es. tachycardia in humans. In an example...

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Hauptverfasser: KOEPPE,HERBERT,DR, STAEHLE,HELMUT,DR, TRAUNECKER,WERNER,DR, ZEILE,KARL, KUMMER,WERNER,DR
Format: Patent
Sprache:eng ; ger
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Zusammenfassung:Title cpd. (I) and its acid-addn. salts, are pref. pred. by reacting a cpd. (II): with sec. butylamine in ethanol (whwere Z is or -CH(OH)-CH2-hal). Cpd. (I) may be used in treatment and prophylaxis of coronary diseases and in the treatment of heart arrythmias es. tachycardia in humans. In an example, (I) is prepd. from 1-(3-hydroxymethylphenoxy)-2,3-epoxypropane and sec. butylamine.