DNA encoding peptide(s) from papilloma virus major capsid protein

DNA (I) encodes a peptide (II) from a papilloma virus (PV) major capsid protein. (II) is any of 11 sequences reproduced (together with the DNA encoding them), or is derived from these sequences by alteration of \- 1 amino acid (aa). (I) is produced by: (i) isolating total DNA from a biopsy of an epi...

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Bibliographische Detailangaben
Hauptverfasser:	BENTON, CLAIRE., EDINGBURGH, GB, VILLIERS-ZUR HAUSEN, ETHEL-MICHEL DE-BIOL. DR., 69483 WALD-MICHELBACH, DE, LAVERGNE, DONNA, 67592 FLOERSHEIM-DALSHEIM, DE, ZUR HAUSEN, HARALD, DR.MED. DR.H.C.MULT., 69483 WALD-MICHELBACH, DE
Format:	Patent
Sprache:	eng ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	DNA (I) encodes a peptide (II) from a papilloma virus (PV) major capsid protein. (II) is any of 11 sequences reproduced (together with the DNA encoding them), or is derived from these sequences by alteration of \- 1 amino acid (aa). (I) is produced by: (i) isolating total DNA from a biopsy of an epithelial neoplasm; (ii) hybridising this with DNA encoding a (II) to detect presence of a PV genome in the total DNA, and (iii) cloning the PV genome into a vector for sequencing. Also claimed are: (1) proteins (III) encoded by (I); (2) expression vectors containing DNA encoding (III); (3) transformants containing (2), and (4) antibodies (Ab) against (III).