New amino-imidazole substituted amino acid derivatives

2-Amino-imidazol-4-yl N-(hetero)arylsulphonyl-amino acid amides (I), their stereoisomers, mixtures and salts are new: A = 1-6C alkylene; or 3-6C alkenylene with the double bond alpha to the imidazole ring; R1 = Ph optionally monosubstituted by alkyl, alkoxy, NMe2, NEt2, NO2, NH2, CN, CF3, F, Cl, Br or I; Ph disubstituted by alkyl or alkoxy; Ph substituted by 1 NH2 and 2 Cl or Br; 1- or 2-naphthyl optionally monosubstituted by alkyl, alkoxy, NMe2, NEt2 or Cl; 1- or 2-naphthyl disubstituted by alkyl or alkoxy; quinolin-8-yl or isoquinolin-5, -6- or -7-yl optionally monosubstituted by alkyl; isoindolin-5-yl-, 1,2,3,4-tetrahydroquinolin-8-yl, 1,2,3,4-tetrahydro-isoquinolin-5-, -6- or -7-yl or 2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl optionally monosubstituted by alkyl in the non-aromatic ring; 5,6,7,8-tetrahydro(1 or 2)naphthyl; anthracen-1-yl; anthraquinon-1-yl; 9H-fluoren-3-yl; dibenzofuran-2- or 4-yl; 9H-xanthen-2-yl; dibenzothiophen-2-yl; or phenoxathiin-2-yl; R2 = H; Me; or Y1-CO-1-3C alkyl; Y1 = OH; alkoxy; benzyloxy; NH2; NH(alkyl); or N(alkyl)2; R3 = H or Me; R4 = 1-6C alkyl; 3-6C alkenyl; 3-7C cycloalkyl; alkoxyalkyl; benzyl; tetrahydrofuran-2-ylmethyl; or tetrahydropyran-2-ylmethyl; R5 = H; 1-6C alkyl; 3-6C alkenyl; Y1-CO-1-3C alkyl; or (p-Y1-CO-C6H4)-1-3C alkyl; or NR4R5 = 4-6C alkyleneimino optionally monosubstituted by alkyl, alkoxy or W or disubstituted by alkyl and W; W = HOCH2-; alkoxy-CH2-; (alkyl or alkoxy)-CO-O-CH2-; H2N-CH2-; alkyl-NH-CH2-; benzyl-NH-CH2-; (alkyl, alkoxy or benzyloxy)-CO-NH-CH2-; (alkyl or benzyl)2N-CH2-; CN; 1H-tetrazol-5-yl; or Y2-CO-; Y2 = OH; alkoxy; NH2; NH(alkyl or benzyl); N(alkyl or benzyl)2; or (carboxyalkyl, alkoxycarbonyl or benzyloxycarbonylalkyl)amino; and unspecified alkyl and alkylene contain 1-4C.