Heterocyclische Dioxetan-Substrate, Verfahren zur Herstellung und Verwendung

The invention concerns compounds of general formulae (Ia) and (Ib), in which R and R , which may be identical or different, designate hydrogen, C1-C6 lower alkyl, straight-chain or branched, or an aryl group, optionally substituted by electron-attracting groups, R means a cleavable group, W designat...

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Bibliographische Detailangaben
Hauptverfasser:	HERRMANN, RUPPERT. DR., 82362 WEILHEIM, DE, WEISS, DIETER. DR., 07743 JENA, DE, JOSEL, HANS-PETER. DR., 82362 WEILHEIM, DE, HEINDL, DIETER. DR., 81549 MUENCHEN, DE, BECKERT, RAINER, ., 07751 JENA, DE, ADAM, WALDEMAR, DR., 97074 WUERZBURG, DE, ELTZ, HERBERT VON DER. DR., 82362 WEILHEIM, DE, HOELTKE, HANS-JOACHIM-BIOL. DR., 82377 PENZBERG, DE
Format:	Patent
Sprache:	ger
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY ORGANIC CHEMISTRY PHYSICS STEROIDS TESTING
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Beschreibung
Zusammenfassung:	The invention concerns compounds of general formulae (Ia) and (Ib), in which R and R , which may be identical or different, designate hydrogen, C1-C6 lower alkyl, straight-chain or branched, or an aryl group, optionally substituted by electron-attracting groups, R means a cleavable group, W designates hydrogen, halogen or a pseudohalogen, at least one of the groups R and R designates a group stabilizing the dioxethane structure, at most one of the groups R and R designating hydrogen, and X or Y designating oxygen, N-R or C(R)2, R having the meanings given for R or R , or a mesomeric double bond or a carbonyl group, and n being 0 or 1 and m being 1 or 2. The invention further concerns a process for preparing these compounds. The compounds are novel and can be used as substrates in immunological assays and DNA diagnoses using colour-forming activating agents.