Vakzine zur Therapie von AIDS, und Verfahren zur Herstellung

Vaccine for preventing HIV infection and/or treating AIDS contains inactivated HIV particles that are produced by: (a) culturing HIV in a medium contg. the radioactive 32P isotope as P source; (b) isolating HIV particles from the medium while retaining at least 50% of the gp120 antigen; (c) storing...

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Hauptverfasser: STENGOLD, EFIM S., MOSKAU/MOSKVA, RU, SERGEEV, OLEG V., MOSKAU/MOSKVA, RU, GARAEV, MANSUR M., MOSKAU/MOSKVA, RU, GODIN, EUGENE A.., MOSKAU/MOSKVA, RU
Format: Patent
Sprache:ger
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Zusammenfassung:Vaccine for preventing HIV infection and/or treating AIDS contains inactivated HIV particles that are produced by: (a) culturing HIV in a medium contg. the radioactive 32P isotope as P source; (b) isolating HIV particles from the medium while retaining at least 50% of the gp120 antigen; (c) storing the particles (in which the RNA has at least one phosphodiester bond that includes 32P) for > 2 months at -70 degrees C or lower, and opt. (d) formulating the stored particles into a vaccine.