Neue Arylglycinamidderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen

The invention concerns novel aryl glycinamide derivatives of general formula (I) and pharmaceutically acceptable salts thereof, the symbols having the following meanings: R and R together with the nitrogen atom to which they are bound form a ring of formula (II) shown in which p is 2 or 3 and X stan...

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Bibliographische Detailangaben
Hauptverfasser:	JUNG, BIRGIT., 55411 BINGEN, DE, SPECK, GEORG. DR., 55218 INGELHEIM, DE, BRIEM, HANS., 55257 BUDENHEIM, DE, SCHNORRENBERG, GERD. DR., 55435 GAU-ALGESHEIM, DE, ESSER, FRANZ. DR., 55218 INGELHEIM, DE, DOLLINGER, HORST. DR., 55218 INGELHEIM, DE
Format:	Patent
Sprache:	ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention concerns novel aryl glycinamide derivatives of general formula (I) and pharmaceutically acceptable salts thereof, the symbols having the following meanings: R and R together with the nitrogen atom to which they are bound form a ring of formula (II) shown in which p is 2 or 3 and X stands for oxygen, N(CH2)nR or CR R ; and R , R , R , R , R , R , Ar and n have the meanings indicated in the description. The invention also concerns the production and use of these substances. The novel compounds are valuable neurokinin (tachykinin) antagonists.