Cyclic parathyroid hormone fragments with lactam bridge

Cyclic parathyroid hormone fragments with lactam bridge

New cyclic parathyroid hormone fragments (CPTH) have the amino acid sequence of h, b, p, r or cPTH(1-34), opt. extended by up to 4 amino acids (aa) at the C-terminus and opt. shortened by up to 3 amino acids at the N-terminus, and are cyclised between positions 13 and 17. One of these positions is o...

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Bibliographische Detailangaben
Hauptverfasser: HONOLD, KONRAD-BIOL. DR., 82377 PENZBERG, DE, DONY, CAROLA-BIOL. DR., 81477 MUENCHEN, DE, ESSWEIN, ANGELIKA. DR., 78224 SINGEN, DE, SCHAEFER, WOLFGANG. DR., 68199 MANNHEIM, DE, HOFFMANN, EIKE. DR., 68519 VIERNHEIM, DE
Format: Patent
Sprache:eng ; ger
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:New cyclic parathyroid hormone fragments (CPTH) have the amino acid sequence of h, b, p, r or cPTH(1-34), opt. extended by up to 4 amino acids (aa) at the C-terminus and opt. shortened by up to 3 amino acids at the N-terminus, and are cyclised between positions 13 and 17. One of these positions is occupied by L- or D- Orn or Lys, and the other by L- or D- Glu or Asp.