Verfahren zur Herstellung von Ergotamin und Ergocryptin

Described is a microbiological process for the preparation of ergotamine and ergocryptine. The process is characterized in that Claviceps purpurea FI 32/17 is cultivated under aerobic conditions in submerged culture in a liquid nutrient medium containing an assimilable source of carbon, an assimilab...

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Hauptverfasser: MARIA AMICI,ALBA, MINGHETTI,ANACLETO, SPALLA,CELESTINO,-LANDW, SCOTTI,TULLIO,-LANDW
Format: Patent
Sprache:ger
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Zusammenfassung:Described is a microbiological process for the preparation of ergotamine and ergocryptine. The process is characterized in that Claviceps purpurea FI 32/17 is cultivated under aerobic conditions in submerged culture in a liquid nutrient medium containing an assimilable source of carbon, an assimilable source of nitrogen and mineral salts. The cultivation is carried out at from 20 DEG to 35 DEG C. with a pH of from 4.5 to 6.5. Claviceps purpurea FI 32/17 has been given the index number ATCC 20102 by the American Type Culture Collection, Rockville, Maryland.