Verfahren zur Herstellung von Cephalosporinderivaten

Betaine (Ie is prepd. by reacting the hydronitrate with a base, pref. an organic one with a pKb of 6 or less, particularly a liquid tertiary or secondary amine: (where R1 is H; R2 is acyl and X is quaternary ammonium). Specifically claimed is N-(7-21-thienylacetamido-cepth-3-em-3-ylmethyl)pyridinium...

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Hauptverfasser: STOCKER,GABRIELLE, GIBSON LONG,ALAN, JOHN SHARP,CHRISTOPHER, ALFRED WILKINSON,PETER, ALFRED CRISP,HAROLD, EARDLEY,STEPHEN, FRANCIS OUGHTON,JOHN
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Sprache:ger
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Zusammenfassung:Betaine (Ie is prepd. by reacting the hydronitrate with a base, pref. an organic one with a pKb of 6 or less, particularly a liquid tertiary or secondary amine: (where R1 is H; R2 is acyl and X is quaternary ammonium). Specifically claimed is N-(7-21-thienylacetamido-cepth-3-em-3-ylmethyl)pyridinium-4-carbo- xylate.