Pharmaceutical compositions, useful e.g. for the treatment of neurodegenerative diseases, psychiatric or neuropathological diseases or especially pain and epilepsy, comprise N,N'-disubstituted piperazine derivatives

Pharmaceutical compositions comprising N,N'-disubstituted piperazine derivatives (I) are new. Pharmaceutical compositions comprising N,N'-disubstituted piperazine derivatives of formula (I), in the form of diastereomers, enantiomers or their mixtures (including racemates) and free bases, s...

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Bibliographische Detailangaben
Hauptverfasser: SUNDERMANN, BERND, MAUL, CORINNA, HAURAND, MICHAEL, CHIZH, BORIS, URAGG, HEINZ, BUSCHMANN, HELMUT DR
Format: Patent
Sprache:eng ; ger
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Zusammenfassung:Pharmaceutical compositions comprising N,N'-disubstituted piperazine derivatives (I) are new. Pharmaceutical compositions comprising N,N'-disubstituted piperazine derivatives of formula (I), in the form of diastereomers, enantiomers or their mixtures (including racemates) and free bases, salts or solvates, optionally together with auxiliaries, are new. R , R = linear or branched, saturated or unsaturated aliphatic residue; R +R = (CH2)n; n = integer; R , R = linear or branched, saturated or unsaturated aliphatic residue, saturated or unsaturated cycloaliphatic residue, aryl or heteroaryl (the ring systems are optionally substituted and optionally bonded via a linear or branched, saturated or unsaturated aliphatic bridge, the aryl or heteroaryl residues optionally being part of a polycyclic system); and R = H; or aryl or heteroaryl (both optionally substituted and optionally forming part of a polycyclic system). The invention relates to a pharmaceutical containing N,N'-disubstituted piperazine compounds and to the use of said compounds for producing a pharmaceutical. Die vorliegende Erfindung betrifft Arzneimittel, enthaltend N,N'-disubstituierte Piperazin-Verbindungen und die Verwendung dieser Verbindungen zur Herstellung eines Arzneimittels.