RETROVIRALE PROTEASEHEMMER

The invention relates to compounds of the formula in which AAN is a divalent radical which consists of one to five divalent alpha -amino acid residues and which is connected at the N terminus to the radical R and at the C terminus to the group NH-, AAC is a divalent radical which consists of one or...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	FAESSLER,ALEXANDER,CH, SCHNEIDER,PETER,CH, RUEGER,HEINRICH,CH, HUNGERBUEHLER,ERNST,CH
Format:	Patent
Sprache:	ger
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to compounds of the formula in which AAN is a divalent radical which consists of one to five divalent alpha -amino acid residues and which is connected at the N terminus to the radical R and at the C terminus to the group NH-, AAC is a divalent radical which consists of one or two divalent alpha -amino acid residues and which is connected at the N terminus to the group -C=O and at the C terminus to the radical R , R is hydroxyl, etherified hydroxyl, amino or substituted amino with the exception of an amino radical derived from an alpha -amino acid, and R is hydrogen or an acyl radical with the exception of an optionally N-substituted acyl radical of a natural amino acid, and salts of such compounds with salt-forming groups. The compounds are suitable as gag protease inhibitors.