VERFAHREN ZUR HERSTELLUNG VON DIHYDROPYRIDINEN

New compounds useful as therapeutical agent and useful as intermediates for the preparation of other therapeutically active dihydropyridines. which new compounds are of the formula wherein R is one or two (the same or different) substituents on the phenyl ring selected from the group consisting of l...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: LJUNG, BENGT R. ,SE, BERNTSSON, PEDER B. ,SE, CARLSSON, STIG A. I. ,SE
Format: Patent
Sprache:ger
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:New compounds useful as therapeutical agent and useful as intermediates for the preparation of other therapeutically active dihydropyridines. which new compounds are of the formula wherein R is one or two (the same or different) substituents on the phenyl ring selected from the group consisting of lower alkyl, NO2, CN, CF3, Cl and Br; A is a straight or branched alkylene group with 2-5 carbon atoms; R is wherein B is a straight or branched alkylene group with 2-5 carbon atoms and R and R are the same or different and each represents a straight or branched alkyl group with 1-5 carbon atoms, an alkylaryl group or both together are part of a 5-7membered heterocyclic ring; R is a straight or branched alkyl group with 1-5 carbon atoms in which alkyl group the carbon chain is interrupted by an oxygen atom; R is a lower alkyl group, or a physiologically acceptable salt or optical isomer thereof, processes for the preparation of said compounds; pharmaceutical preparations containing said compounds, a method for their therapeutical use and a new process using said compounds as intermediates.