Verfahren zur Herstellung detoxifizierter Zubereitungen von Cytostatika

The present invention is related to a process for producing a pharmaceutical preparation containing a cytostatically active alkylating agent which has been detoxified by adding thereto a a pharmacologically acceptable salt of a mercapto alkane sulfonic acid of the general formula HS-alk-SO3H wherein...

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1. Verfasser: BROCK NORBERT DR
Format: Patent
Sprache:ger
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Zusammenfassung:The present invention is related to a process for producing a pharmaceutical preparation containing a cytostatically active alkylating agent which has been detoxified by adding thereto a a pharmacologically acceptable salt of a mercapto alkane sulfonic acid of the general formula HS-alk-SO3H wherein alk is an alkylene group having from 2 to 6 carbon atoms, in an amount of at least 20 % of the weight of the alkylating agent thereby substantially improving the properties thereof.