VIRUS INACTIVATION METHOD IN THE PRESENCE OF POLYALKYLENE GLYCOL, AS WELL AS OBTAINED PHARMACEUTICAL PREPARATION

PCT No. PCT/IB95/00019 Sec. 371 Date Jun. 28, 1996 Sec. 102(e) Date Jun. 28, 1996 PCT Filed Jan. 10, 1995 PCT Pub. No. WO95/09657 PCT Pub. Date Apr. 13, 1995The invention relates to a pharmaceutical preparation comprising a plasma protein wherein said preparation is free of infectious agents as well...

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Hauptverfasser:	DORNER FRIEDRICH, BARRETT NOEL DR, EIBL JOHANN DR
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:	PCT No. PCT/IB95/00019 Sec. 371 Date Jun. 28, 1996 Sec. 102(e) Date Jun. 28, 1996 PCT Filed Jan. 10, 1995 PCT Pub. No. WO95/09657 PCT Pub. Date Apr. 13, 1995The invention relates to a pharmaceutical preparation comprising a plasma protein wherein said preparation is free of infectious agents as well as essentially free of denaturation products and is obtainable by a method that encompasses the following steps: a) addition of a polyether and a chaotropic agent to a solution comprising the plasma protein, optional lyophilization of the solution; b) inactivation of infectious agents in the presence of the polyether by a physio-chemical or chemical treatment, and c) removal of the polyether and the chaotropic agent.