PHARMACEUTICAL COMPOUNDS

The invention provides novel cryptophycin compounds which can be useful for disrupting the microtubulin system, as anti-neoplastic agents, and for the treatment of cancer. The invention further provides a formulation for administering the novel cryptophycin compounds.

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Bibliographische Detailangaben
Hauptverfasser:	MARTINELLI MICHAEL JOHN, EHLHARDT WILLIAM JOSEPH, GOTTUMUKKALA SUBBARAJU VENKATA, RAY JAMES EDWARD, MOORE RICHARD ELLIOTT, PATEL VINOD FRANCIS, VASUDEVAN VENKATRAGHAVAN, NORMAN BRYAN HURST, SHIH CHUAN, TOTH JOHN ELDON, MUNROE JOHN EDWIN, AL-AWAR RIMA SALIM, MOHER ERIC DAVID
Format:	Patent
Sprache:	cze ; eng
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	The invention provides novel cryptophycin compounds which can be useful for disrupting the microtubulin system, as anti-neoplastic agents, and for the treatment of cancer. The invention further provides a formulation for administering the novel cryptophycin compounds.