PROCESS FOR PREPARING 1,2,3,9-TETRAHYDRO-9-METHYL-3-£(2-METHYL-1H-IMIDAZOL-1-YL)-METHYL| -4H-CARBAZOL-4-ONE

PROCESS FOR PREPARING 1,2,3,9-TETRAHYDRO-9-METHYL-3-£(2-METHYL-1H-IMIDAZOL-1-YL)-METHYL| -4H-CARBAZOL-4-ONE

Process for the preparation of 1,2,3,9-tetrahydro-9- methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol- 4-one of the formula I comprising the cyclization of the compound of the formula II under the conditions of a Friedel-Crafts acylation by activating the carboxyl group by acid catalysis in...

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Bibliographische Detailangaben
Hauptverfasser: GES JOSE MARIA CALDERO, CLOTET JUAN HUGUET
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Process for the preparation of 1,2,3,9-tetrahydro-9- methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol- 4-one of the formula I comprising the cyclization of the compound of the formula II under the conditions of a Friedel-Crafts acylation by activating the carboxyl group by acid catalysis in a suitable solvent medium and finally isolating the required products by conventional means.