DIARYLPIPERIDINE ESTERS OF 1,4-DIHYDROPYRIDINE DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEREOF
Diaryl compounds of formula I (I) wherein Ar represents a ring of the formula in which Y denotes oxygen (O), sulfur (S), vinylene (-CH=CH-), azomethine (-CH=N-) or a group of the formula R1, R2 and R3 are identical or different and denote hydrogen, C1-C6-alkyl, C3-C7-alkoxyalkyl, aryl, aryl-C1-C6-al...
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creator | ULRICH WOLF-RUDIGER DR EISTETTER KLAUS DR KILIAN ULRICH DR KLEMM KURT DR FLOCKERZI DIETER DR BEUME ROLF DR ELTZE MANFRID DR SANDERS KARL DR KOLASSA NORBERT DR AMSCHLER HERMANN DR |
description | Diaryl compounds of formula I (I) wherein Ar represents a ring of the formula in which Y denotes oxygen (O), sulfur (S), vinylene (-CH=CH-), azomethine (-CH=N-) or a group of the formula R1, R2 and R3 are identical or different and denote hydrogen, C1-C6-alkyl, C3-C7-alkoxyalkyl, aryl, aryl-C1-C6-alkyl or aryloxy-C1-C6-alkyl, R4 and R5 are identical or different and denote hydrogen, hydroxyl, halogen, nitro, cyano, trifluoromethyl, C1-C4-alkyl, C1-C4-alkoxy, C1-C4-alkoxy which is completely or partly substituted by fluorine, C1-C4-alkoxycarbonyl, C2-C5-acyl, amino or mono- or di-C1-C4-alkylamino, R6, R7, R8 and R9 are identical or different and denote hydrogen, hydroxyl, halogen, C1-C4-alkyl, C1-C4-alkoxy, amino, mono- or di-C1-C4-alkylamino, or C1-C4-alkoxy which is completely or partly substituted by fluorine, and A denotes straight-chain or branched C2-C5-alkylene, which can be substituted by C1-C4-alkoxy or aryl, and their salts are new compounds for the treatment and prophylaxis of diseases of circulatory origin. |
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EISTETTER KLAUS DR ; KILIAN ULRICH DR ; KLEMM KURT DR ; FLOCKERZI DIETER DR ; BEUME ROLF DR ; ELTZE MANFRID DR ; SANDERS KARL DR ; KOLASSA NORBERT DR ; AMSCHLER HERMANN DR</creatorcontrib><description>Diaryl compounds of formula I (I) wherein Ar represents a ring of the formula in which Y denotes oxygen (O), sulfur (S), vinylene (-CH=CH-), azomethine (-CH=N-) or a group of the formula R1, R2 and R3 are identical or different and denote hydrogen, C1-C6-alkyl, C3-C7-alkoxyalkyl, aryl, aryl-C1-C6-alkyl or aryloxy-C1-C6-alkyl, R4 and R5 are identical or different and denote hydrogen, hydroxyl, halogen, nitro, cyano, trifluoromethyl, C1-C4-alkyl, C1-C4-alkoxy, C1-C4-alkoxy which is completely or partly substituted by fluorine, C1-C4-alkoxycarbonyl, C2-C5-acyl, amino or mono- or di-C1-C4-alkylamino, R6, R7, R8 and R9 are identical or different and denote hydrogen, hydroxyl, halogen, C1-C4-alkyl, C1-C4-alkoxy, amino, mono- or di-C1-C4-alkylamino, or C1-C4-alkoxy which is completely or partly substituted by fluorine, and A denotes straight-chain or branched C2-C5-alkylene, which can be substituted by C1-C4-alkoxy or aryl, and their salts are new compounds for the treatment and prophylaxis of diseases of circulatory origin.</description><edition>5</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1993</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19931013&DB=EPODOC&CC=CZ&NR=396691A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19931013&DB=EPODOC&CC=CZ&NR=396691A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ULRICH WOLF-RUDIGER DR</creatorcontrib><creatorcontrib>EISTETTER KLAUS DR</creatorcontrib><creatorcontrib>KILIAN ULRICH DR</creatorcontrib><creatorcontrib>KLEMM KURT DR</creatorcontrib><creatorcontrib>FLOCKERZI DIETER DR</creatorcontrib><creatorcontrib>BEUME ROLF DR</creatorcontrib><creatorcontrib>ELTZE MANFRID DR</creatorcontrib><creatorcontrib>SANDERS KARL DR</creatorcontrib><creatorcontrib>KOLASSA NORBERT DR</creatorcontrib><creatorcontrib>AMSCHLER HERMANN DR</creatorcontrib><title>DIARYLPIPERIDINE ESTERS OF 1,4-DIHYDROPYRIDINE DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEREOF</title><description>Diaryl compounds of formula I (I) wherein Ar represents a ring of the formula in which Y denotes oxygen (O), sulfur (S), vinylene (-CH=CH-), azomethine (-CH=N-) or a group of the formula R1, R2 and R3 are identical or different and denote hydrogen, C1-C6-alkyl, C3-C7-alkoxyalkyl, aryl, aryl-C1-C6-alkyl or aryloxy-C1-C6-alkyl, R4 and R5 are identical or different and denote hydrogen, hydroxyl, halogen, nitro, cyano, trifluoromethyl, C1-C4-alkyl, C1-C4-alkoxy, C1-C4-alkoxy which is completely or partly substituted by fluorine, C1-C4-alkoxycarbonyl, C2-C5-acyl, amino or mono- or di-C1-C4-alkylamino, R6, R7, R8 and R9 are identical or different and denote hydrogen, hydroxyl, halogen, C1-C4-alkyl, C1-C4-alkoxy, amino, mono- or di-C1-C4-alkylamino, or C1-C4-alkoxy which is completely or partly substituted by fluorine, and A denotes straight-chain or branched C2-C5-alkylene, which can be substituted by C1-C4-alkoxy or aryl, and their salts are new compounds for the treatment and prophylaxis of diseases of circulatory origin.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1993</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFyr8KwjAQgPEuDqI-g_cAdiiVguORXM1BTcIlFupSisTJP4X6_tihu9M3_L519tKM0jWePQlrtgQUIkkAV0NxOOaaTafF-W5RPW8tRm4pAFoN3qBcUNE1ssIGvJBHmd3ZAMrZiGzZniEaEnL1Nls9hueUdks32b6mqEyexk-fpnG4p3f69upWnqrqVGBZ_j9-mNs2yw</recordid><startdate>19931013</startdate><enddate>19931013</enddate><creator>ULRICH WOLF-RUDIGER DR</creator><creator>EISTETTER KLAUS DR</creator><creator>KILIAN ULRICH DR</creator><creator>KLEMM KURT DR</creator><creator>FLOCKERZI DIETER DR</creator><creator>BEUME ROLF DR</creator><creator>ELTZE MANFRID DR</creator><creator>SANDERS KARL DR</creator><creator>KOLASSA NORBERT DR</creator><creator>AMSCHLER HERMANN DR</creator><scope>EVB</scope></search><sort><creationdate>19931013</creationdate><title>DIARYLPIPERIDINE ESTERS OF 1,4-DIHYDROPYRIDINE DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEREOF</title><author>ULRICH WOLF-RUDIGER DR ; EISTETTER KLAUS DR ; KILIAN ULRICH DR ; KLEMM KURT DR ; FLOCKERZI DIETER DR ; BEUME ROLF DR ; ELTZE MANFRID DR ; SANDERS KARL DR ; KOLASSA NORBERT DR ; AMSCHLER HERMANN DR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CZ396691A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1993</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ULRICH WOLF-RUDIGER DR</creatorcontrib><creatorcontrib>EISTETTER KLAUS DR</creatorcontrib><creatorcontrib>KILIAN ULRICH DR</creatorcontrib><creatorcontrib>KLEMM KURT DR</creatorcontrib><creatorcontrib>FLOCKERZI DIETER DR</creatorcontrib><creatorcontrib>BEUME ROLF DR</creatorcontrib><creatorcontrib>ELTZE MANFRID DR</creatorcontrib><creatorcontrib>SANDERS KARL DR</creatorcontrib><creatorcontrib>KOLASSA NORBERT DR</creatorcontrib><creatorcontrib>AMSCHLER HERMANN DR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ULRICH WOLF-RUDIGER DR</au><au>EISTETTER KLAUS DR</au><au>KILIAN ULRICH DR</au><au>KLEMM KURT DR</au><au>FLOCKERZI DIETER DR</au><au>BEUME ROLF DR</au><au>ELTZE MANFRID DR</au><au>SANDERS KARL DR</au><au>KOLASSA NORBERT DR</au><au>AMSCHLER HERMANN DR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DIARYLPIPERIDINE ESTERS OF 1,4-DIHYDROPYRIDINE DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEREOF</title><date>1993-10-13</date><risdate>1993</risdate><abstract>Diaryl compounds of formula I (I) wherein Ar represents a ring of the formula in which Y denotes oxygen (O), sulfur (S), vinylene (-CH=CH-), azomethine (-CH=N-) or a group of the formula R1, R2 and R3 are identical or different and denote hydrogen, C1-C6-alkyl, C3-C7-alkoxyalkyl, aryl, aryl-C1-C6-alkyl or aryloxy-C1-C6-alkyl, R4 and R5 are identical or different and denote hydrogen, hydroxyl, halogen, nitro, cyano, trifluoromethyl, C1-C4-alkyl, C1-C4-alkoxy, C1-C4-alkoxy which is completely or partly substituted by fluorine, C1-C4-alkoxycarbonyl, C2-C5-acyl, amino or mono- or di-C1-C4-alkylamino, R6, R7, R8 and R9 are identical or different and denote hydrogen, hydroxyl, halogen, C1-C4-alkyl, C1-C4-alkoxy, amino, mono- or di-C1-C4-alkylamino, or C1-C4-alkoxy which is completely or partly substituted by fluorine, and A denotes straight-chain or branched C2-C5-alkylene, which can be substituted by C1-C4-alkoxy or aryl, and their salts are new compounds for the treatment and prophylaxis of diseases of circulatory origin.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | DIARYLPIPERIDINE ESTERS OF 1,4-DIHYDROPYRIDINE DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEREOF |
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