DIARYLPIPERIDINE ESTERS OF 1,4-DIHYDROPYRIDINE DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEREOF
Diaryl compounds of formula I (I) wherein Ar represents a ring of the formula in which Y denotes oxygen (O), sulfur (S), vinylene (-CH=CH-), azomethine (-CH=N-) or a group of the formula R1, R2 and R3 are identical or different and denote hydrogen, C1-C6-alkyl, C3-C7-alkoxyalkyl, aryl, aryl-C1-C6-al...
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Format: | Patent |
Sprache: | eng |
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Zusammenfassung: | Diaryl compounds of formula I (I) wherein Ar represents a ring of the formula in which Y denotes oxygen (O), sulfur (S), vinylene (-CH=CH-), azomethine (-CH=N-) or a group of the formula R1, R2 and R3 are identical or different and denote hydrogen, C1-C6-alkyl, C3-C7-alkoxyalkyl, aryl, aryl-C1-C6-alkyl or aryloxy-C1-C6-alkyl, R4 and R5 are identical or different and denote hydrogen, hydroxyl, halogen, nitro, cyano, trifluoromethyl, C1-C4-alkyl, C1-C4-alkoxy, C1-C4-alkoxy which is completely or partly substituted by fluorine, C1-C4-alkoxycarbonyl, C2-C5-acyl, amino or mono- or di-C1-C4-alkylamino, R6, R7, R8 and R9 are identical or different and denote hydrogen, hydroxyl, halogen, C1-C4-alkyl, C1-C4-alkoxy, amino, mono- or di-C1-C4-alkylamino, or C1-C4-alkoxy which is completely or partly substituted by fluorine, and A denotes straight-chain or branched C2-C5-alkylene, which can be substituted by C1-C4-alkoxy or aryl, and their salts are new compounds for the treatment and prophylaxis of diseases of circulatory origin. |
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