AMIDES OF QUINOLYLMETHOXYPHENYLACETIC ACID

Quinolylmethoxyphenyl-acetamides of the formula: rogen, hydroxyl, halogen, cyano, carboxyl, nitro, trifluoromethyl, trifluoromethoxy, alkyl, alkoxy or optionally substituted aryl; R1 represents optionally substituted cycloalkyl; and R2 and R3 independently represent hydrogen, alkyl, benzyl, or optio...

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Hauptverfasser: MATZKE MICHAEL DR, HATZELMANN ARMIN DR, MULLER-PEDDINGHAUS REINER DR, RADDATZ SIEGFRIED DR, MOHRS KLAUS-HELMUT DR, FRUCHTMANN ROMANIS
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creator MATZKE MICHAEL DR
HATZELMANN ARMIN DR
MULLER-PEDDINGHAUS REINER DR
RADDATZ SIEGFRIED DR
MOHRS KLAUS-HELMUT DR
FRUCHTMANN ROMANIS
description Quinolylmethoxyphenyl-acetamides of the formula: rogen, hydroxyl, halogen, cyano, carboxyl, nitro, trifluoromethyl, trifluoromethoxy, alkyl, alkoxy or optionally substituted aryl; R1 represents optionally substituted cycloalkyl; and R2 and R3 independently represent hydrogen, alkyl, benzyl, or optionally substituted cycloalkyl; or together represent piperidinyl, morpholino, or piperazinyl; show a high in vitro activity as leukotriene synthesis inhibitors and, therefore, are suitable for the treatment and prevention of inflammations.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title AMIDES OF QUINOLYLMETHOXYPHENYLACETIC ACID
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