CYCLOALKYL-SUBSTITUTED AND HETEROCYCLOALKYL-SUBSTITUTED DERIVATIVES OF IMIDAZOLYLPROPENIC ACID

CYCLOALKYL-SUBSTITUTED AND HETEROCYCLOALKYL-SUBSTITUTED DERIVATIVES OF IMIDAZOLYLPROPENIC ACID

Cycloalkyl- and heterocyclyl-substituted imidazolylpropenoic acid derivatives can be prepared by reaction of imidazolylaldehydes with appropriate carboxylic acid derivatives and subsequent dehydrogenation. The compounds can be employed as active ingredients in medicaments, in particular for the trea...

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Hauptverfasser: KNORR ANDREAS DR, MULLER-GLIEMANN MATTHIAS DR, FEY PETER DR, HUBSCH WALTER DR, KAZDA STANISLAV DR, WOHLFEIL STEFAN DR, DRESSEL JURGEN PH.D, STASCH JOHANNES-PETER DR, KRAMER THOMAS DR, BEUCK MARTIN DR, HANKO RUDOLF DR, MULLER ULRICH DR
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Cycloalkyl- and heterocyclyl-substituted imidazolylpropenoic acid derivatives can be prepared by reaction of imidazolylaldehydes with appropriate carboxylic acid derivatives and subsequent dehydrogenation. The compounds can be employed as active ingredients in medicaments, in particular for the treatment of hypertension and atherosclerosis.