CONSTRUCTION OF EXPRESSIVE VECTORS FOR THE EXPRESSION OF ANTI-MEDIATOR-RNA AND THEIR USE, TRANSFICATED CELLS CONTAINING SUCH CONSTRUCTIONS AND MEDICAMENTS BASED THEREON

The present invention relates to the targeted blocking of the genetic information of the viral messenger ribonucleic acid (mRNA) for virus replication (e.g. of HIV) in transfected, haemopoietic cells with particularly suitable expression systems which express a complementary antisense RNA.

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Bibliographische Detailangaben
Hauptverfasser: STRUCK MARK-MICHAEL DR, ANTONICEK HORST-PETER DR, LOEBBERDING ANTONIUS DR, STROPP UDO DR, SPRINGER WOLFGANG DR, BIESERT LOTHAR DR, KRETSCHMER AXEL DR, BAUMGARTEN JORG DR, MIELKE BURKHARD DR, RUBSAMEN-WAIGMANN HELGA DR, HAUSNER THOMAS-PETER DR, SUHARTONO HARY DR
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to the targeted blocking of the genetic information of the viral messenger ribonucleic acid (mRNA) for virus replication (e.g. of HIV) in transfected, haemopoietic cells with particularly suitable expression systems which express a complementary antisense RNA.