DERIVATIVES OF PURIN-6-ONE, PROCESS OF THEIR PREPARATION, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF AND THEIR USE

Purin-6-one derivatives of formula (I) are new: R = H or 1-8C alkyl; R = 1-4C acyl or 1-8C alkyl (optionally substituted); A = 1-6C alkylene or 2-6C alkenylene; D, L = 6-10C aryl or 5-7 membered aromatic (optionally benzo-condensed) heterocycle with 1-3 heteroatoms (N, S and/or O) (optionally substi...

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Hauptverfasser:	PERZBORN ELISABETH DR, BISCHOFF ERWIN DR, NIEWOHNER ULRICH DR, HUTTER JOACHIM DR, SCHUTZ HELMUT DR
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Purin-6-one derivatives of formula (I) are new: R = H or 1-8C alkyl; R = 1-4C acyl or 1-8C alkyl (optionally substituted); A = 1-6C alkylene or 2-6C alkenylene; D, L = 6-10C aryl or 5-7 membered aromatic (optionally benzo-condensed) heterocycle with 1-3 heteroatoms (N, S and/or O) (optionally substituted by 1-3 halo, OH, NO2, CF3, carboxy, 1-6C alkyl, 1-6C alkoxy, 1-6C alkoxycarbonyl, etc.; or D = a group or formula (D); E = CH2YZ; Y = a bond, O, S or NH; Z = 1-5C alkylene.