PROCESS FOR PREPARING DRY INJECTIONS OF CIS-DIAMINEDICHLOROPLATINUM COMPLEX

The invention concerns a Process for preparing a medicament containing cis-DDP and excipients sodium chloride, manitol and hydrocarbon for modification of pH. Defined in detail are individual phases of production, based on controlled and automatic freeze-drying of water, leading to a very well disso...

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Bibliographische Detailangaben
Hauptverfasser: KUDLACEK ALES, KASPAREK JAN, KUBACKOVA MARTA RNDR, ZAVODNA IVANKA RNDR, NOVOTNY JIRI, KISS FRANTISEK
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention concerns a Process for preparing a medicament containing cis-DDP and excipients sodium chloride, manitol and hydrocarbon for modification of pH. Defined in detail are individual phases of production, based on controlled and automatic freeze-drying of water, leading to a very well dissoluble lyophilised product, suitable for intravenous application. The process is suitable from economic and hygienic reasons.