Oxazolidinone derivative, process of its preparation and pharmaceutical preparation in it is comprised

Deriv t oxazolidinonu obecn ho vzorce I, kde znamen R.sup.1.n. fenyl substituovan² CN, H.sub.2.n.N-CH.sub.2.n.-, H.sub.2.n.N-C(=NH)- a H.sub.2.n.N-C(=NH)-NH-CH.sub.2.n., B skupinu a), A C.sub.1-6.n.alkyl, R.sup.2.n. atom H nebo skupinu A, R.sup.3.n. atom H nebo skupinu (CH.sub.2.n.).sub.n.n.-COOR.su...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: JURASZYK HORST DR, BERNOTAT-DANIELOWSKI SABINE DR, WURZIGER HANNS DR, RADDATZ PETER DR, MELZER GUIDO DR, GANTE JOACHIM DR
Format: Patent
Sprache:cze ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Deriv t oxazolidinonu obecn ho vzorce I, kde znamen R.sup.1.n. fenyl substituovan² CN, H.sub.2.n.N-CH.sub.2.n.-, H.sub.2.n.N-C(=NH)- a H.sub.2.n.N-C(=NH)-NH-CH.sub.2.n., B skupinu a), A C.sub.1-6.n.alkyl, R.sup.2.n. atom H nebo skupinu A, R.sup.3.n. atom H nebo skupinu (CH.sub.2.n.).sub.n.n.-COOR.sup.2.n., E CH, n 0 nebo 1, a jeho enantiomery a fyziologicky p°ijateln soli jsou vhodn pro v²robu farmaceutick²ch prost°edk pro l en tromb z, srde n ch infarkt , apoplexie, osteopor zy, arterioskler zy, z n t a/nebo n dor .\ In the present invention there is disclosed an oxazolidinone derivative of the general formula I, wherein Re1 represents phenyl being substituted with CN, Hi2N-CHi2-, Hi2N-C(=NH)- and Hi2N-C(=NH)-NH-CHi2, B represents the group a), and alkyl containing 1 to 6 carbon atoms, Re2 represents a hydrogen atom H or the group A, Re3 represents a hydrogen atom or the group (CHi2)in-COORe2, E CH, n is 0 or 1. The derivative and enantiomers thereof as well as its physiologically acceptable salts are useful for preparation of pharmaceutical preparations intended for treating thromboses, heart attacks, apoplexy, osteoporosis, arteriosclerosis, inflammations and/or tumors.